DoseResponse fit curve

Description

Nonlinear regression of paired concentration-response measurements to the Hill sigmoidal (4PL) model: f(x) = Emin + (Emax - Emin) / (1 + (EC50/x)^n). Returns the four fitted parameters (baseline Emin, plateau Emax, midpoint EC50, Hill exponent n) with standard errors, 95% CI for EC50, coefficient of determination R2, and predicted response at each measured concentration. Requires at least 4 positive concentration inputs. Useful for characterising pharmacological potency and assessing assay da...

Quick Install

Installation

pip install tooluniverse

Tags