DrugSynergy calculate ci

Description

Calculate Chou-Talalay Combination Index (CI) for drug synergy quantification. CI is derived from the Median Effect Equation: fa/fu = (D/Dm)^m. CI < 1 indicates synergy, CI = 1 is additive, CI > 1 is antagonism. Also computes the Dose Reduction Index (DRI) showing how much each drug dose can be reduced in combination. Supports both mutually exclusive (drugs with similar mechanisms) and mutually non-exclusive (drugs with different mechanisms) assumptions. Based on Chou & Talalay (1984). Use fo...

Quick Install

Installation

pip install tooluniverse

Tags