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Pharmacy Safe Moderate Evidence

NCA compute parameters

by Harvard MIMS Lab (ToolUniverse)

Description

Perform Non-Compartmental Analysis (NCA) on time-concentration pharmacokinetic data. Computes key PK parameters: Cmax (peak concentration), Tmax (time to peak), AUC0-t (area under curve to last measured point using linear-log trapezoidal method), AUC0-inf (extrapolated), terminal elimination half-life (t½), elimination rate constant (λz), clearance (CL), and volume of distribution (Vd) when dose is provided. Follows FDA/EMA NCA guidelines. Use this when you have raw plasma concentration vs. t...

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Installation

pip install tooluniverse

Status

Published

Reviewer

Automated import

Date Added

2026-03-30

Tags

tooluniverse nca pharmacokinetics non-compartmental-analysis